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Skeletons point to Columbus voyage for syphilis origins

"The evidence keeps accumulating that a progenitor of syphilis came from the New World with Columbus' crew and rapidly evolved," says anthropologist George Armelagos.

Skeletons don’t lie. But sometimes they may mislead, as in the case of bones that reputedly showed evidence of syphilis in Europe and other parts of the Old World before Christopher Columbus made his historic voyage in 1492.

None of this skeletal evidence, including 54 published reports, holds up when subjected to standardized analyses for both diagnosis and dating, according to an appraisal in the current Yearbook of Physical Anthropology. In fact, the skeletal data bolsters the case that syphilis did not exist in Europe before Columbus set sail.

“This is the first time that all 54 of these cases have been evaluated systematically,” says George Armelagos, an anthropologist at Emory University and co-author of the appraisal. “The evidence keeps accumulating that a progenitor of syphilis came from the New World with Columbus’ crew and rapidly evolved into the venereal disease that remains with us today.”

The appraisal was led by two of Armelagos’ former graduate students at Emory: Molly Zuckerman, who is now an assistant professor at Mississippi State University, and Kristin Harper, currently a post-doctoral fellow at Columbia University. Additional authors include Emory anthropologist John Kingston and Megan Harper from the University of Missouri.

“Syphilis has been around for 500 years,” Zuckerman says. “People started debating where it came from shortly afterwards, and they haven’t stopped since. It was one of the first global diseases, and understanding where it came from and how it spread may help us combat diseases today.”

The history of syphilis, and society's reactions to the disease, have eerie parallels to the more modern story of HIV/AIDS.

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